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Senior Scientist, Protein Engineering & Structural Biology

Company

Careers 2005

Location

Rockville, United States

Type

Full-time

Our biotech client is expanding their world-class Antibody Engineering group and seeking an exceptional scientist with deep expertise in structural biology and protein engineering, with a strong drive to apply structural insight to antibody discovery and optimization.

The ideal candidate will take on the following tasks:


· Leverage cryo-EM, X-ray crystallography, and complementary biophysical techniques to elucidate antibody-antigen interactions, define epitope architecture, and inform structure-guided engineering decisions.
· Apply protein structure/function expertise to challenging drug targets — including membrane proteins and conformational epitopes — translating structural knowledge into actionable engineering hypotheses.
· Partner closely with antibody engineering colleagues to integrate structural data into discovery and optimization campaigns, driving rational lead progression.
· Develop and advance computational a...

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