The Institute for Digital Molecular Analytics and Science (IDMxS), officially launched on 1 December 2022, is a Research Centre of Excellence (RCE) supported by a total investment of around S$160 million over 10 years. IDMxS' overarching approach is to go beyond the neat simplicity of intermolecular interactions in dilute media and embrace the inherent complexity of biological interactions and dense heterogeneity of their environments.
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We are seeking a highly motivated and creative Research Fellow to join our team and lead an exciting project on how biomolecular condensates regulate enzyme function. We use quantitative single-molecule approaches to link enzyme structure, dynamics, and kinetics in both condensate and dilute environments. By integrating complementary measurements across timescales, we investigate conformational state switching, reaction dynamics under non-equilibrium conditions, and molecular mobility and permeability within dense ...