Are you passionate about immunology, inflammation, and cutting-edge translational research? We are offering a fully funded PhD position to investigate how metabolic signals shape neutrophil phenotype and function during inflammation and infection.
Our research focuses on how soluble metabolites such as uric acid drive neutrophil dysfunction and contribute to the increased risk of infection in kidney disease.
The successful candidate will study the cellular and molecular mechanisms by which uric acid regulates key neutrophil functions, including phagocytosis, migration, oxidative stress, bacterial killing and neutrophil extracellular trap (NET) formation.
The project combines translational and mechanistic approaches, including: isolation and functional characterization of neutrophils from patients with kidney disease, advanced flow cytometry and functional immune assays, gene-editing approaches, molecular biology techniq...
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